PUMA BIOTECHNOLOGY INC (PBYI)
PHARMACEUTICAL PREPARATIONS
PUMA BIOTECHNOLOGY INC (PBYI) is listed on Nasdaq, where it has traded since March 21, 2012.
- Listed On
- Nasdaq
- Listed Since
- March 21, 2012
- Employees
- 179
- Market Cap
- $504M
About PUMA BIOTECHNOLOGY INC
Puma Biotechnology Inc is a biopharmaceutical company that develops and commercializes inventive products to enhance cancer care and improve treatment outcomes for patients. It is currently commercializing NERLYNX, an oral version of neratinib, for the treatment of HER2-positive breast cancer. Also, it is developing Alisertib, a selective, small-molecule inhibitor of aurora kinase A that is designed to disrupt mitosis, resulting in apoptosis of rapidly proliferating tumor cells that are dependent on aurora kinase A.
Institutional ownership
In 13F filings for the quarter ended June 30, 2026, 156 institutions reported holding PBYI, with 38.7 million shares worth $313.6 million in aggregate. The largest reported holder was Acorn Capital Advisors, with 4.1 million shares worth $33.5 million. Of the 5 largest holders listed below, 4 added shares and 1 held its position unchanged during the quarter.
| Institution | Shares | Value | Quarter change |
|---|---|---|---|
| Acorn Capital Advisors | 4,131,299 | $34M | Unchanged |
| Vanguard | 3,986,987 | $32M | Added 4.01% |
| BlackRock | 3,804,736 | $31M | Added 5.72% |
| American Century Companies | 2,319,996 | $19M | Added 21.06% |
| Acadian Asset Management | 2,053,523 | $17M | Added 0.58% |
Form 13F is a quarterly report that institutional investment managers with at least $100 million in qualifying securities file with the SEC. It lists long positions as of the last day of the quarter and is due within 45 days of quarter end, so these holdings describe that date rather than today.
Frequently asked questions
What is PBYI?
PUMA BIOTECHNOLOGY INC (PBYI) is listed on Nasdaq, where it has traded since March 21, 2012.
Who are the largest institutional holders of PBYI?
In 13F filings for the quarter ended June 30, 2026, the largest reported holders of PBYI were Acorn Capital Advisors, Vanguard and BlackRock.
How many institutions own PBYI?
156 institutions reported a position in PBYI for the quarter ended June 30, 2026, worth $313.6 million in total.
Did institutions buy or sell PBYI last quarter?
Of the 5 largest reported holders, 4 added shares and 1 held its position unchanged during the quarter. Every reported holder and its change is on the SentiSense ownership page for PBYI.
Every reported institutional holder, plus insider and congressional trades in PBYI, on SentiSense.