Septerna, Inc. Common Stock (SEPN) Ownership & Trading Activity

Institutional holders, insider transactions, and congressional trades for SEPN. 13F holdings as of 2026-06-30.

In 13F filings for the quarter ended June 30, 2026, 148 institutions reported holding SEPN, with 47.2 million shares worth $1.6 billion in aggregate.

Top Institutional Holders

InstitutionSharesValueChange
RA Capital Management6,995,858$234MUNCHANGED
Trv GP V6,215,591$208MUNCHANGED
Driehaus Capital Management4,433,058$148MINCREASED
Trv GP VI4,211,659$141MUNCHANGED
Samsara Biocapital3,149,128$105MUNCHANGED

Full institutional holdings, insider history, and congressional trades for Septerna, Inc. Common Stock on SentiSense.