Sionna Therapeutics, Inc. Common Stock (SION)

PHARMACEUTICAL PREPARATIONS

Sionna Therapeutics, Inc. Common Stock (SION) is listed on Nasdaq, where it has traded since February 7, 2025.

Listed On
Nasdaq
Listed Since
February 7, 2025
Employees
59
Market Cap
$183M

About Sionna Therapeutics, Inc. Common Stock

Sionna Therapeutics Inc is a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) patients by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein to deliver clinically meaningful benefits to CF patients. CF is a progressive and life-threatening genetic disease caused by inherited mutations in the CFTR gene, which heads to insufficient CFTR function. The Company is managed as one operating segment focused on the research and development of cystic fibrosis therapies.

Institutional ownership

In 13F filings for the quarter ended June 30, 2026, 141 institutions reported holding SION, with 48.1 million shares worth $2.1 billion in aggregate. The largest reported holder was RA Capital Management, with 9.9 million shares worth $435.7 million. Of the 5 largest holders listed below, 1 reduced its position and 4 held their positions unchanged during the quarter.

InstitutionSharesValueQuarter change
RA Capital Management9,905,045$436MUnchanged
Tpg GP a6,494,962$286MUnchanged
Viking Global Investors3,195,181$141MUnchanged
Atlas Venture Life Science Advisors2,995,602$132MUnchanged
Orbimed Advisors2,555,877$112MReduced 27.61%

Form 13F is a quarterly report that institutional investment managers with at least $100 million in qualifying securities file with the SEC. It lists long positions as of the last day of the quarter and is due within 45 days of quarter end, so these holdings describe that date rather than today.

Frequently asked questions

What is SION?

Sionna Therapeutics, Inc. Common Stock (SION) is listed on Nasdaq, where it has traded since February 7, 2025.

Who are the largest institutional holders of SION?

In 13F filings for the quarter ended June 30, 2026, the largest reported holders of SION were RA Capital Management, Tpg GP a and Viking Global Investors.

How many institutions own SION?

141 institutions reported a position in SION for the quarter ended June 30, 2026, worth $2.1 billion in total.

Did institutions buy or sell SION last quarter?

Of the 5 largest reported holders, 1 reduced its position and 4 held their positions unchanged during the quarter. Every reported holder and its change is on the SentiSense ownership page for SION.

Every reported institutional holder, plus insider and congressional trades in SION, on SentiSense.