Spero Therapeutics, Inc. Common Stock (SPRO) Ownership & Trading Activity

Institutional holders, insider transactions, and congressional trades for SPRO. 13F holdings as of 2026-06-30.

In 13F filings for the quarter ended June 30, 2026, 59 institutions reported holding SPRO, with 21.5 million shares worth $47.5 million in aggregate.

Top Institutional Holders

InstitutionSharesValueChange
Gsk9,190,606$20MUNCHANGED
Pfizer2,362,348$5MUNCHANGED
Vanguard2,349,320$5MINCREASED
Renaissance Technologies947,904$2MDECREASED
Alphabet889,979$2MUNCHANGED

Full institutional holdings, insider history, and congressional trades for Spero Therapeutics, Inc. Common Stock on SentiSense.