Spyre Therapeutics, Inc. Common Stock (SYRE) Ownership & Trading Activity

Institutional holders, insider transactions, and congressional trades for SYRE. 13F holdings as of 2026-06-30.

Top Institutional Holders

InstitutionSharesValueChange
BlackRock6,506,605$578MINCREASED
State Street3,057,416$271MINCREASED
Remedium Capital Partners1,464,169$130MINCREASED
Pictet Asset Management Holding628,138$56MINCREASED
Emerald Advisers567,430$50MDECREASED

Recent Insider Trades

InsiderTypeSharesValueDate
Cameron Turtle (Chief Executive Officer)SELL16$2K2026-08-03
Cameron Turtle (Chief Executive Officer)SELL1,392$135K2026-08-03
Cameron Turtle (Chief Executive Officer)SELL5,635$541K2026-08-03
Cameron Turtle (Chief Executive Officer)SELL7,157$681K2026-08-03
Cameron Turtle (Chief Executive Officer)SELL800$75K2026-08-03

Full institutional holdings, insider history, and congressional trades for Spyre Therapeutics, Inc. Common Stock on SentiSense.