Upstream Bio, Inc. Common Stock (UPB) Ownership & Trading Activity
Institutional holders, insider transactions, and congressional trades for UPB. 13F holdings as of 2026-06-30.
In 13F filings for the quarter ended June 30, 2026, 143 institutions reported holding UPB, with 50.6 million shares worth $350.1 million in aggregate.
Top Institutional Holders
| Institution | Shares | Value | Change |
|---|---|---|---|
| FMR | 8,162,897 | $56M | INCREASED |
| Orbimed Advisors | 5,693,589 | $39M | UNCHANGED |
| Norges Bank | 3,768,619 | $26M | NEW |
| BlackRock | 3,753,358 | $26M | INCREASED |
| Vanguard | 2,868,896 | $20M | INCREASED |
Full institutional holdings, insider history, and congressional trades for Upstream Bio, Inc. Common Stock on SentiSense.