Septerna, Inc. Common Stock (SEPN)
PHARMACEUTICAL PREPARATIONS
Septerna, Inc. Common Stock (SEPN) is listed on Nasdaq, where it has traded since October 25, 2024.
- Listed On
- Nasdaq
- Listed Since
- October 25, 2024
- Employees
- 130
- Market Cap
- $2.1B
About Septerna, Inc. Common Stock
Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.
Institutional ownership
In 13F filings for the quarter ended June 30, 2026, 148 institutions reported holding SEPN, with 47.2 million shares worth $1.6 billion in aggregate. The largest reported holder was RA Capital Management, with 7.0 million shares worth $234.3 million. Of the 5 largest holders listed below, 1 added shares and 4 held their positions unchanged during the quarter.
| Institution | Shares | Value | Quarter change |
|---|---|---|---|
| RA Capital Management | 6,995,858 | $234M | Unchanged |
| Trv GP V | 6,215,591 | $208M | Unchanged |
| Driehaus Capital Management | 4,433,058 | $148M | Added 0.85% |
| Trv GP VI | 4,211,659 | $141M | Unchanged |
| Samsara Biocapital | 3,149,128 | $105M | Unchanged |
Form 13F is a quarterly report that institutional investment managers with at least $100 million in qualifying securities file with the SEC. It lists long positions as of the last day of the quarter and is due within 45 days of quarter end, so these holdings describe that date rather than today.
Frequently asked questions
What is SEPN?
Septerna, Inc. Common Stock (SEPN) is listed on Nasdaq, where it has traded since October 25, 2024.
Who are the largest institutional holders of SEPN?
In 13F filings for the quarter ended June 30, 2026, the largest reported holders of SEPN were RA Capital Management, Trv GP V and Driehaus Capital Management.
How many institutions own SEPN?
148 institutions reported a position in SEPN for the quarter ended June 30, 2026, worth $1.6 billion in total.
Did institutions buy or sell SEPN last quarter?
Of the 5 largest reported holders, 1 added shares and 4 held their positions unchanged during the quarter. Every reported holder and its change is on the SentiSense ownership page for SEPN.
Every reported institutional holder, plus insider and congressional trades in SEPN, on SentiSense.